Description

3-Pyridinemethanol,6-Chloro-5-Fluoro is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily targeted at research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate within their product pipelines.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging its halogenated pyridine core for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in regulatory submissions.

Basic Information

Product Name	3-Pyridinemethanol,6-Chloro-5-Fluoro
CAS No.	1174028-24-0
Molecular Formula	C6H5ClFNO
Molecular Weight	161.56 g/mol
Synonyms	(6-Chloro-5-fluoropyridin-3-yl)methanol; 6-Chloro-5-fluoro-3-pyridinemethanol; 6-Chloro-5-fluoropyridine-3-methanol; 3-(Hydroxymethyl)-6-chloro-5-fluoropyridine; 5-Fluoro-6-chloro-3-pyridinemethanol; 6-Chloro-5-fluoro-3-hydroxymethylpyridine; 6-Chloro-5-fluoro-3-pyridylmethanol
EINECS	Contact for details

Quality Control

Our 3-Pyridinemethanol,6-Chloro-5-Fluoro is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.