Description

Bromo 2,3,4,6-Tetra-o-Acetyl-α-D-Glucopyranoside-13C6 is a stable, isotopically labeled glycosyl donor, specifically a peracetylated glucopyranosyl bromide with uniform carbon-13 labeling at all six carbon positions. This compound is a critical reagent for the synthesis of 13C-labeled oligosaccharides, glycoconjugates, and complex carbohydrates, enabling advanced research in metabolic tracing and structural analysis. It is essential for pharmaceutical, biotechnology, and academic research laboratories focused on glycoscience, drug discovery, and the development of labeled standards for mass spectrometry.

Application

• Synthesis of 13C-labeled oligosaccharides and glycans for use as internal standards in quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy.
• Preparation of isotopically labeled glycoconjugates and glycoproteins for metabolic pathway tracing and pharmacokinetic studies in drug development.
• Key building block in carbohydrate chemistry research, facilitating mechanistic studies of glycosylation reactions and enzyme activities.
• Production of labeled standards for use in analytical method development and validation within quality control laboratories.
• Research tool in structural biology to elucidate the three-dimensional structure and dynamics of complex carbohydrates.
• Substrate for glycosyltransferase assays in enzymatic studies and high-throughput screening for drug discovery.

Basic Information

Product Name	Bromo 2,3,4,6-Tetra-o-Acetyl-α-D-Glucopyranoside-13C6
CAS No.	1173694-36-4
Molecular Formula	C1413C6H19BrO9
Molecular Weight	~467.2 g/mol (for 13C6 labeled form)
Synonyms	2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl bromide-13C6; Acetobromo-α-D-glucose-13C6; α-D-Glucopyranosyl bromide, 2,3,4,6-tetraacetate-13C6; Bromo-2,3,4,6-tetra-O-acetyl-α-D-glucopyranose-13C6; Peracetylated α-D-glucosyl bromide-13C6; 13C6-Acetobromoglucose; α-Acetobromoglucose-13C6; (2R,3R,4S,5R,6R)-2-(Acetyloxy)-6-(bromomethyl)-3,4,5-tris(acetyloxy)tetrahydro-2H-pyran-13C6
EINECS	Contact for details

Quality Control

Our isotopically labeled compounds are manufactured under strict quality protocols to ensure high chemical and isotopic purity, critical for sensitive analytical applications. Each batch is characterized by NMR and MS to confirm structure and isotopic enrichment. We provide comprehensive Certificates of Analysis (COA) detailing purity, assay, and 13C isotopic abundance, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a desiccated environment to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure (1H, 13C)
Purity (HPLC)	≥ 95%
Isotopic Enrichment (MS)	≥ 99 atom % 13C
Chemical Purity (NMR)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.