Description

Sodium Dichloroacetate-13C2 is a stable isotope-labeled analog of sodium dichloroacetate, where two carbon atoms are replaced with the 13C isotope. This product is essential for advanced research requiring precise metabolic tracing and quantification in complex biological systems. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and contract research organizations (CROs) working in the fields of metabolomics, pharmacokinetics, and drug mechanism studies.

Application

• Internal standard for the accurate quantification of sodium dichloroacetate (DCA) in biological matrices via LC-MS or GC-MS.
• Tracer compound in metabolic flux analysis to study the pyruvate dehydrogenase kinase (PDK) pathway and cellular energy metabolism.
• Critical reagent in the development and validation of bioanalytical methods for preclinical and clinical studies involving DCA.
• Use in stable isotope-resolved metabolomics (SIRM) to investigate cancer metabolism, mitochondrial disorders, and other disease states.
• Chemical reference standard for quality control and regulatory compliance in pharmaceutical manufacturing.
• Tool compound for investigating the pharmacokinetics, pharmacodynamics, and metabolic fate of dichloroacetate.

Basic Information

Product Name	Sodium Dichloroacetate-13C2
CAS No.	1173022-90-6
Molecular Formula	13C2Cl2HNaO2
Molecular Weight	152.90 g/mol (approx.)
Synonyms	Sodium Dichloroacetate-13C2; Sodium Dichloroacetate (13C2); DCA-13C2 Sodium Salt; Dichloroacetic-13C2 Acid Sodium Salt; Sodium 2,2-Dichloroacetate-13C2; 13C2-Labeled Sodium Dichloroacetate; [13C2]-Sodium Dichloroacetate; NSC 126313-13C2
EINECS	Contact for details

Quality Control

Our Sodium Dichloroacetate-13C2 is manufactured under strict quality systems to ensure high chemical and isotopic purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (atom % 13C), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We adhere to relevant industry standards for stable isotope-labeled compounds to guarantee batch-to-batch consistency and reliability for your research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Handle and store under inert conditions if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (Titration)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.