Description

3,6-Dichloro-2-Hydroxybenzoic-[13C6] Acid is a stable isotope-labeled analog of 3,6-dichloro-2-hydroxybenzoic acid, where all six carbon atoms are the non-radioactive carbon-13 isotope. This compound is essential as a high-purity internal standard and reference material for precise quantitative analysis in mass spectrometry. It is primarily required by analytical laboratories and research institutions in the pharmaceutical, agrochemical, and environmental science sectors for method development, validation, and ensuring accurate measurement of its unlabeled counterpart in complex matrices.

Application

• Internal Standard for LC-MS/MS: Used for the accurate quantification of 3,6-dichloro-2-hydroxybenzoic acid and related metabolites in pharmacokinetic and bioanalytical studies.
• Metabolite Tracing: Enables the study of metabolic pathways and degradation products in plant, animal, and environmental systems.
• Method Development & Validation: Serves as a critical reference standard for developing and validating robust analytical methods in compliance with GLP and FDA guidelines.
• Environmental Analysis: Employed in trace-level detection and quantification of chlorinated phenolic pollutants in water and soil samples.
• Isotope Dilution Mass Spectrometry (IDMS): Provides the highest accuracy in quantitative analysis, correcting for sample loss and instrument variability.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradants in active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3,6-Dichloro-2-Hydroxybenzoic-[13C6] Acid
CAS No.	1173019-34-5
Molecular Formula	13C6H4Cl2O3
Molecular Weight	~213.00 (based on 13C6)
Synonyms	3,6-Dichloro-2-hydroxybenzoic-13C6 acid; 2-Hydroxy-3,6-dichlorobenzoic-13C6 acid; 3,6-Dichlorosalicylic-13C6 acid; [13C6]-3,6-Dichloro-2-hydroxybenzoic acid; Isotopically Labeled 3,6-Dichlorosalicylic Acid; 13C6 3,6-Dichloro-2-HBA; 3,6-Dichloro-2-HBA-13C6; Stable Isotope Labeled Internal Standard CAS 1173019-34-5
EINECS	Contact for details

Quality Control

Every batch of 3,6-Dichloro-2-Hydroxybenzoic-[13C6] Acid is produced and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR and mass spectrometry to confirm structure and isotopic enrichment. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and specific tests. Our quality commitment ensures the material is suitable for the most demanding analytical applications, including those requiring compliance with GMP/GLP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment (13C)	≥99 atom % 13C
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.