Description

Sulfamethoxypyridazine-D3 is a deuterium-labeled analog of the sulfonamide antibiotic sulfamethoxypyridazine, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity, isotopically labeled compound is essential for ensuring accuracy and reliability in mass spectrometry-based analyses, such as LC-MS/MS, by correcting for variations in sample preparation and instrument response. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, environmental monitoring, and food safety sectors who require precise quantification of sulfamethoxypyridazine or related compounds.

Application

• Internal Standard for LC-MS/MS Analysis: Primary use as a quantitative reference standard in bioanalytical and environmental testing.
• Pharmaceutical Research & Development: Used in pharmacokinetic (PK) and pharmacodynamic (PD) studies, metabolism research, and drug impurity profiling.
• Veterinary Drug Residue Analysis: Critical for ensuring food safety by accurately detecting sulfamethoxypyridazine residues in meat, milk, and other animal products.
• Environmental Monitoring: Enables precise tracking and quantification of antibiotic pollutants in water and soil samples.
• Clinical Diagnostics: Supports the development of robust assays for therapeutic drug monitoring (TDM).
• Method Development & Validation: Serves as a key component in establishing and validating new analytical protocols for regulatory compliance.

Basic Information

Product Name	Sulfamethoxypyridazine-D3
CAS No.	1172846-03-5
Molecular Formula	C11H9D3N4O3S
Molecular Weight	283.32 g/mol (for D3 isotopologue)
Synonyms	4-Amino-N-(6-methoxy-3-pyridazinyl)benzenesulfonamide-D3; Sulfamethoxypyridazine-d3; Deuterated Sulfamethoxypyridazine; SMP-D3; [2H3]-Sulfamethoxypyridazine; N1-(6-Methoxy-3-pyridazinyl)sulfanilamide-D3; SMP Internal Standard; Isotopically Labeled Sulfamethoxypyridazine
EINECS	Contact for details

Quality Control

Every batch of Sulfamethoxypyridazine-D3 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, verified by advanced spectroscopic and chromatographic techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing batch-specific data for purity, isotopic enrichment, and solvent content to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the material should be handled in a dry environment and the container kept sealed to prevent moisture absorption, which could affect stability and analytical performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.