Description

2-(3-Fluoro-4-Methyl-Benzyl)-Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct molecular structure. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for synthesizing new chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes during drug discovery.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Reference Standard: Can be utilized as an analytical standard for method development and quality control in API manufacturing.
• Custom Synthesis: A foundational compound for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and fluorine-containing compounds.

Basic Information

Product Name	2-(3-Fluoro-4-Methyl-Benzyl)-Piperidine Hydrochloride
CAS No.	1172829-38-7
Molecular Formula	C14H20ClFN
Molecular Weight	257.77 g/mol
Synonyms	2-[(3-Fluoro-4-methylphenyl)methyl]piperidine hydrochloride; 1-(3-Fluoro-4-methylbenzyl)piperidine hydrochloride; Piperidine, 2-[(3-fluoro-4-methylphenyl)methyl]-, hydrochloride (1:1); 2-(3-Fluoro-4-methylbenzyl)piperidine HCl; 1172829-38-7
EINECS	Contact for details

Quality Control

Our 2-(3-Fluoro-4-Methyl-Benzyl)-Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.