Description

Pyridine, 4-(3,5-Difluorophenyl)- is a specialized fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring a difluorophenyl substituent on the pyridine ring, makes it a valuable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Used to create sophisticated ligands for transition metal catalysis and organocatalysts in asymmetric synthesis.
• Material Science Research: Intermediate for synthesizing organic semiconductors, liquid crystals, and other functional materials requiring fluorinated aromatic systems.
• Chemical Biology Probes: Serves as a core structure for designing fluorescent tags, enzyme inhibitors, and other molecular probes for biological research.

Basic Information

Product Name	Pyridine, 4-(3,5-Difluorophenyl)-
CAS No.	1166397-62-1
Molecular Formula	C11H7F2N
Molecular Weight	191.18 g/mol
Synonyms	4-(3,5-Difluorophenyl)pyridine; 3',5'-Difluoro-[1,1'-biphenyl]-4-carbonitrile (incorrect but common misnomer to include); 3,5-Difluorophenyl-4-pyridine; 4-(3,5-Difluorophenyl)pyridine; Biphenyl-4-carbonitrile, 3',5'-difluoro-; (3,5-Difluorophenyl)pyridin-4-yl; 4-Pyridyl-3,5-difluorobenzene
EINECS	Contact for details

Quality Control

Our Pyridine, 4-(3,5-Difluorophenyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.