Description

5-(Trifluoromethyl)Pyridin-2-Ylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to introduce the versatile 5-(trifluoromethyl)pyridin-2-yl moiety into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethylpyridine scaffolds, which are prevalent in drug discovery for their metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as those for OLEDs and semiconductors, where its structure can tune electronic properties.
• Chemical Biology & Probe Design: Useful for creating molecular probes and bioconjugates for studying biological systems and diagnostic applications.

Basic Information

Product Name	5-(Trifluoromethyl)Pyridin-2-Ylboronic Acid
CAS No.	1162257-58-0
Molecular Formula	C6H5BF3NO2
Molecular Weight	190.92 g/mol
Synonyms	2-Borono-5-(trifluoromethyl)pyridine; [5-(Trifluoromethyl)pyridin-2-yl]boronic Acid; 5-(Trifluoromethyl)-2-pyridineboronic Acid; 5-Trifluoromethylpyridine-2-boronic Acid; 2-Pyridineboronic acid, 5-(trifluoromethyl)-; (5-Trifluoromethyl-2-pyridyl)boronic Acid
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)Pyridin-2-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.