Description

4-Amino-5-Chloro-n-(1-(3-Methoxypropyl)Piperidin-4-Yl)-2,3-Dihydrobenzofuran-7-Carboxamide Hydrate is a high-purity, complex heterocyclic compound serving as a critical intermediate in advanced pharmaceutical synthesis. Its value lies in providing a reliable and consistent building block for research and development, enabling the creation of novel therapeutic agents. This product is essential for pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical suppliers targeting the development of new chemical entities, particularly in central nervous system (CNS) and receptor-targeted drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for receptor-targeted therapies.
• Drug Discovery & Development: Used in medicinal chemistry for lead optimization and the creation of compound libraries for high-throughput screening.
• Biochemical Research: Serves as a reference standard or a precursor in pharmacological studies investigating specific receptor interactions and signal transduction pathways.
• Contract Research & Manufacturing: Supplied to CROs and CMOs engaged in custom synthesis and scale-up projects for preclinical and clinical trial materials.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis to introduce complex piperidine and benzofuran motifs into target molecules.

Basic Information

Product Name	4-Amino-5-Chloro-n-(1-(3-Methoxypropyl)Piperidin-4-Yl)-2,3-Dihydrobenzofuran-7-Carboxamide Hydrate
CAS No.	1161952-84-6
Molecular Formula	C18H25ClN4O3 · xH2O
Molecular Weight	380.87 g/mol (Anhydrous basis)
Synonyms	4-Amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide hydrate; UNII-0K0V6S2Z4I; 0K0V6S2Z4I; 4-Amino-5-chloro-N-(1-(3-methoxypropyl)-4-piperidinyl)-2,3-dihydro-7-benzofurancarboxamide hydrate; Benzofuran-7-carboxamide, 4-amino-5-chloro-N-[1-(3-methoxypropyl)-4-piperidinyl]-2,3-dihydro-, hydrate (1:?); CAS 1161952-84-6
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Chloro-n-(1-(3-Methoxypropyl)Piperidin-4-Yl)-2,3-Dihydrobenzofuran-7-Carboxamide Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.