Description

2-Fluoro-5-Methylnicotinaldehyde is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic introduction of both fluorine and an aldehyde functional group onto the nicotinic acid scaffold, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used to create novel fluorinated pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile starting material for constructing complex chelating ligands and organocatalysts in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty chemicals and functional materials, such as liquid crystals and organic semiconductors.
• Chemical Biology Probes: Utilized to create fluorinated analogs of natural products for mechanism-of-action and metabolic pathway studies.

Basic Information

Product Name	2-Fluoro-5-Methylnicotinaldehyde
CAS No.	1160993-95-2
Molecular Formula	C7H6FNO
Molecular Weight	139.13 g/mol
Synonyms	5-Methyl-2-fluoronicotinaldehyde; 2-Fluoro-5-methyl-3-pyridinecarboxaldehyde; 3-Pyridinecarboxaldehyde, 2-fluoro-5-methyl-; 2-Fluoro-5-methylpyridine-3-carbaldehyde; 1160993-95-2
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methylnicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.