Description

2-Chloro-3,5-Dibromo-6-Fluorotoluene is a halogenated toluene derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and highly functionalized building block, enabling the precise introduction of multiple halogen atoms into complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring specific halogen substitution patterns for bioactivity.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the halogen atoms contribute to binding efficacy and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of novel organometallic complexes and catalysts for cross-coupling and other transition metal-mediated reactions.
• Fluorine Chemistry Building Block: The presence of the fluorine atom makes it valuable for synthesizing compounds where fluorine substitution is desired to modulate lipophilicity, metabolic stability, and binding affinity.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research projects and scale-up campaigns requiring this specific halogenated scaffold.

Basic Information

Product Name	2-Chloro-3,5-Dibromo-6-Fluorotoluene
CAS No.	1160574-53-7
Molecular Formula	C7H4Br2ClF
Molecular Weight	306.37 g/mol
Synonyms	1-Chloro-2,4-dibromo-3-fluoro-5-methylbenzene; 3,5-Dibromo-2-chloro-6-fluorotoluene; Toluene, 2-chloro-3,5-dibromo-6-fluoro-; 2-Chloro-3,5-dibromo-6-fluoro-1-methylbenzene; 2-Chloro-6-fluoro-3,5-dibromotoluene
EINECS	Contact for details

Quality Control

Our 2-Chloro-3,5-Dibromo-6-Fluorotoluene is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.