Description

5-Bromo-3-Chloro-2-Fluorotoluene is a high-purity halogenated toluene derivative, serving as a critical building block in advanced organic synthesis. Its precise halogen substitution pattern makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the halogen atoms contribute to bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and the exploration of new chemical spaces.
• Dye and Pigment Manufacturing: Intermediate for synthesizing complex halogenated dyes and pigments that require specific light-fastness and color properties.

Basic Information

Product Name	5-Bromo-3-Chloro-2-Fluorotoluene
CAS No.	1160574-49-1
Molecular Formula	C7H5BrClF
Molecular Weight	223.47 g/mol
Synonyms	1-Bromo-5-chloro-3-fluoro-2-methylbenzene; 2-Methyl-5-bromo-3-chloro-1-fluorobenzene; 5-Bromo-3-chloro-2-fluoro-1-methylbenzene; Toluene, 5-bromo-3-chloro-2-fluoro-; 2-Fluoro-5-bromo-3-chlorotoluene; 3-Chloro-5-bromo-2-fluorotoluene
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Chloro-2-Fluorotoluene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.