Description

2,2,2-Trifluoro-1-[1-(2,2,2-Trifluoro-Acetyl)Piperidin-4-Yl]-Ethanone is a high-purity, specialized fluorinated building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique trifluoroacetyl and piperidine motifs impart desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex, fluorine-containing molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) drugs, enzyme inhibitors, and receptor modulators.
• Agrochemical Research: Used in the discovery and synthesis of new-generation herbicides, fungicides, and insecticides that benefit from the enhanced lipophilicity and stability provided by fluorine atoms.
• Fluorinated Ligand Synthesis: Serves as a precursor for creating specialized fluorinated ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes, leveraging the distinct properties of fluorine for detection (e.g., 19F NMR).
• Advanced Material Development: A potential monomer or modifier in the synthesis of specialty polymers and coatings with unique surface properties and chemical resistance.

Basic Information

Product Name	2,2,2-Trifluoro-1-[1-(2,2,2-Trifluoro-Acetyl)Piperidin-4-Yl]-Ethanone
CAS No.	1159982-56-5
Molecular Formula	C9H7F6NO2
Molecular Weight	275.15 g/mol
Synonyms	1,1'-(Piperidine-1,4-diyl)bis(2,2,2-trifluoroethanone); 1,1'-(Piperidine-1,4-diyl)di(2,2,2-trifluoroethanone); 1,4-Bis(trifluoroacetyl)piperidine; 1,4-Piperidinediylbis(2,2,2-trifluoroethanone); 2,2,2-Trifluoro-1-(1-(2,2,2-trifluoroacetyl)piperidin-4-yl)ethan-1-one; 4,4'-Bis(trifluoroacetyl)piperidine; N-(2,2,2-Trifluoroacetyl)-4-(2,2,2-trifluoroacetyl)piperidine
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-[1-(2,2,2-Trifluoro-Acetyl)Piperidin-4-Yl]-Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.