Description

Didesethyl Chloroquine Hydroxyacetamide is a high-purity pharmaceutical intermediate and research chemical. This compound is of significant value in the development and synthesis of novel antimalarial and antiviral agents, serving as a key building block for advanced active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of next-generation chloroquine analogs and related therapeutic compounds.
• Medicinal Chemistry Research: Used as a reference standard and building block in the discovery of new antimalarial and antiviral drug candidates.
• Active Pharmaceutical Ingredient (API) Development: Serves as a key structural component in the manufacturing process of complex APIs.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of quinoline-based drugs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Analytical Standard: Used as a high-purity standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Didesethyl Chloroquine Hydroxyacetamide
CAS No.	1159977-30-6
Molecular Formula	C16H21ClN3O2
Molecular Weight	322.81 g/mol
Synonyms	N-(7-Chloro-4-quinolinyl)-N'-(2-hydroxyethyl)-1,4-pentanediamine; 1-N,4-N-Bis(2-hydroxyethyl)-1-N-(7-chloroquinolin-4-yl)pentane-1,4-diamine; Didesethyl Hydroxychloroquine Impurity; Didesethyl HCQ; Chloroquine Didesethyl Hydroxyacetamide; 4-[(4-[(2-Hydroxyethyl)amino]-1-methylbutyl)amino]-7-chloroquinoline
EINECS	Contact for details

Quality Control

Our Didesethyl Chloroquine Hydroxyacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.