Description

(2,2,2-Trifluoro-1-Pyridin-3-Ylethyl)Amine 2Hcl is a high-purity, fluorinated pyridine derivative supplied as a dihydrochloride salt. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is essential for organizations developing novel active ingredients, particularly in the fields of oncology, neurology, and antiviral therapeutics, where its unique trifluoroethylamine moiety can modulate pharmacokinetic properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for targeted therapies.
• Medicinal Chemistry: Used as a building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Research: Serves as a precursor in the synthesis of novel pesticides and herbicides with enhanced efficacy.
• Ligand Synthesis: Employed in the creation of specialized ligands for catalysis and material science applications.
• Fluorine Chemistry: A valuable reagent for introducing fluorine-containing groups into complex organic molecules to alter their metabolic stability and lipophilicity.

Basic Information

Product Name	(2,2,2-Trifluoro-1-Pyridin-3-Ylethyl)Amine 2Hcl
CAS No.	1159825-86-1
Molecular Formula	C7H8F3N2 • 2HCl
Molecular Weight	273.07 g/mol (Free base: 176.15 g/mol)
Synonyms	3-(2,2,2-Trifluoro-1-aminoethyl)pyridine dihydrochloride; 1-(3-Pyridinyl)-2,2,2-trifluoroethanamine dihydrochloride; 2,2,2-Trifluoro-1-(pyridin-3-yl)ethan-1-amine hydrochloride (1:2); 3-(1-Amino-2,2,2-trifluoroethyl)pyridine dihydrochloride; α-(Trifluoromethyl)-3-pyridinemethanamine dihydrochloride; (2,2,2-Trifluoro-1-(3-pyridinyl)ethyl)amine dihydrochloride
EINECS	Contact for details

Quality Control

Our (2,2,2-Trifluoro-1-Pyridin-3-Ylethyl)Amine 2Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.