Description

4-Bromo-3-Fluoropyridine Hydrochloride is a high-purity halogenated pyridine derivative, a crucial building block in modern organic synthesis. Its value lies in providing a reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce bromine and fluorine substituents at specific positions on a pyridine ring.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the pyridine core is functionalized.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific halogenated heterocycles.

Basic Information

Product Name	4-Bromo-3-Fluoropyridine Hydrochloride
CAS No.	1159811-44-5
Molecular Formula	C5H4BrClFN
Molecular Weight	212.45 g/mol
Synonyms	3-Fluoro-4-bromopyridine hydrochloride; 4-Bromo-3-fluoro-pyridine hydrochloride; Pyridine, 4-bromo-3-fluoro-, hydrochloride (1:1); 4-Bromo-3-fluoropyridine HCl; 4-Bromo-3-fluoropyridinium chloride
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Fluoropyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.