Description

1-Bromo-4-Bromomethyl-2-Trifluoromethyl-Benzene is a high-purity, multi-functional aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both bromine and bromomethyl substituents on a trifluoromethylated benzene ring, makes it a versatile precursor for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethyl and halogenated aromatic motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of novel organic electronic materials, liquid crystals, and polymers where specific halogen and fluorine substitution patterns are critical.
• Cross-Coupling Reactions: Acts as a valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl and complex aromatic systems.
• Functional Group Transformation: The reactive bromomethyl group allows for further derivatization to aldehydes, carboxylic acids, amines, and other functional handles.

Basic Information

Product Name	1-Bromo-4-Bromomethyl-2-Trifluoromethyl-Benzene
CAS No.	1159512-68-1
Molecular Formula	C8H5Br2F3
Molecular Weight	317.93 g/mol
Synonyms	4-Bromobenzyl Bromide, 2-Trifluoromethyl Derivative; 2-Trifluoromethyl-1,4-Dibromomethylbenzene; 1,4-Bis(bromomethyl)-2-(trifluoromethyl)benzene; α,α'-Dibromo-2-(trifluoromethyl)-p-xylene; 2-(Trifluoromethyl)-1,4-bis(bromomethyl)benzene; 4-Bromo-α-bromo-2-(trifluoromethyl)toluene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Bromomethyl-2-Trifluoromethyl-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. This material is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.