Description

3-Bromo-3-(Carboxymethyl)Benzotrifluoride is a versatile trifluoromethylated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, combining a reactive bromine substituent, a carboxylic acid functional group, and the electron-withdrawing trifluoromethyl group, which enables precise structural modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of novel drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the creation of advanced polymers and liquid crystals where the introduction of fluorine atoms can modify thermal stability and optical properties.
• Custom Chemical Synthesis: Provides a versatile handle for medicinal chemistry campaigns, allowing for parallel synthesis and library generation for high-throughput screening.

Basic Information

Product Name	3-Bromo-3-(Carboxymethyl)Benzotrifluoride
CAS No.	1159512-50-1
Molecular Formula	C10H6BrF3O2
Molecular Weight	295.05 g/mol
Synonyms	2-Bromo-α,α,α-trifluoro-m-toluic acid, Acetic acid; 3-Bromo-α,α,α-trifluoro-m-toluic acid; 3-(Bromomethyl)-α,α,α-trifluorobenzoic acid; 3-Bromo-3-(carboxymethyl)benzotrifluoride; [3-(Bromomethyl)phenyl]trifluoromethanone (tautomeric form); m-(Bromomethyl)benzotrifluoride carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Bromo-3-(Carboxymethyl)Benzotrifluoride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.