Description

L-96 is a high-purity specialty chemical identified by CAS NO 1159408-61-3, widely utilized as a critical intermediate in advanced pharmaceutical and agrochemical synthesis. Its structural precision and batch-to-batch consistency enable reliable performance in demanding catalytic and coupling reactions. This compound is essential for R&D laboratories and active pharmaceutical ingredient (API) manufacturers requiring stringent impurity control and reproducible reactivity. Global contract development and manufacturing organizations (CDMOs) and fine chemical producers rely on L-96 for scalable, GMP-aligned processes.

Application

• Key chiral building block in the synthesis of protease inhibitors and antiviral agents
• Intermediate for next-generation herbicides and selective plant growth regulators
• Catalyst ligand precursor in asymmetric cross-coupling reactions (e.g., Suzuki, Heck)
• Structural motif in kinase inhibitor development for oncology therapeutics
• Reference standard in LC-MS and NMR method validation for regulatory submissions
• Functionalized scaffold for peptide mimetic and PROTAC molecule design

Basic Information

Product Name	L-96
CAS No.	1159408-61-3
Molecular Formula	C18H20F3N3O3
Molecular Weight	399.37 g/mol
Synonyms	(2S)-2-[(tert-Butoxycarbonyl)amino]-3-(4-trifluoromethylphenyl)propanoic acid; Boc-L-Phe(4-CF3)-OH; N-[(tert-Butoxy)carbonyl]-L-phenylalanine (4-trifluoromethyl); Boc-(S)-Phe(4-CF3)-OH; (S)-2-(((tert-Butoxy)carbonyl)amino)-3-(4-(trifluoromethyl)phenyl)propanoic acid; L-96; BOC-L-PHE(4-CF3)-OH; TFA-protected L-phenylalanine derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches conform to ACS Reagent Grade specifications and meet ICH Q3A(R2) guidelines for organic impurities. Testing includes identity confirmation (IR, HPLC retention time match), assay (≥99.5% by HPLC), heavy metals (≤10 ppm), residual solvents (per ICH Q3C), and optical purity (enantiomeric excess ≥99.9% ee by chiral HPLC).

Storage

Preserve in a tightly closed container, protected from light. Store at 15–25°C in a dry, well-ventilated area. Due to its hygroscopic nature, minimize exposure to ambient humidity; use desiccant packs during long-term storage. Avoid contact with strong acids, organic solvents, fluorides, or strong alkalis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥99.5%
Optical Purity (Chiral HPLC)	≥99.9% ee
Residue on Ignition	≤0.1%
Water (Karl Fischer)	≤0.5%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	≤0.5% total impurities

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.