Description

(2,6-Difluoropyridin-3-yl)(phenyl)methanone is a high-purity fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its value lies in its unique difluoropyridine scaffold, which is instrumental for modulating the physicochemical and metabolic properties of target molecules. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Serves as a key building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and organocatalysts for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced organic electronic materials, such as charge-transport layers or fluorinated polymers.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	(2,6-Difluoropyridin-3-yl)(phenyl)methanone
CAS No.	1158955-21-5
Molecular Formula	C12H7F2NO
Molecular Weight	219.19 g/mol
Synonyms	3-Benzoyl-2,6-difluoropyridine; Phenyl(2,6-difluoropyridin-3-yl)methanone; 2,6-Difluoro-3-benzoylpyridine; (2,6-Difluoropyridin-3-yl)(phenyl)methanone; 1158955-21-5; Methanone, (2,6-difluoro-3-pyridinyl)phenyl-; (2,6-Difluoro-3-pyridinyl)phenylmethanone
EINECS	Contact for details

Quality Control

Our (2,6-Difluoropyridin-3-yl)(phenyl)methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects with material suitable for research use, pilot plant, and cGMP production scales.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.