Description

1-Isobutyl-1H-Pyrazole-4-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a key building block in advanced organic synthesis. Its primary value lies in its role as a versatile sulfonylation reagent, enabling the efficient introduction of the 1-isobutylpyrazole-4-sulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting various disease pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the pyrazole-sulfonamide structure is a common pharmacophore.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling or modifying biomolecules in probe development and activity-based protein profiling (ABPP).
• Material Science Research: Employed in the creation of specialized polymers or functional materials requiring specific sulfonamide linkages.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to R&D and pilot-scale production.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in medicinal chemistry programs.

Basic Information

Product Name	1-Isobutyl-1H-Pyrazole-4-Sulfonyl Chloride
CAS No.	1156915-65-9
Molecular Formula	C7H11ClN2O2S
Molecular Weight	222.69 g/mol
Synonyms	1-Isobutyl-1H-pyrazole-4-sulfonyl chloride; 1-(2-Methylpropyl)-1H-pyrazole-4-sulfonyl chloride; Pyrazole-4-sulfonyl chloride, 1-isobutyl-; 1H-Pyrazole-4-sulfonyl chloride, 1-isobutyl-; 1156915-65-9; 1-Isobutylpyrazole-4-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 1-Isobutyl-1H-Pyrazole-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.