Description

n-{[3-(Trifluoromethyl)Phenyl]Methyl}Prop-2-Enamide is a specialized organic compound featuring a trifluoromethylphenyl moiety linked to an acrylamide group. This structure makes it a valuable building block and intermediate in advanced chemical synthesis, particularly where the introduction of fluorine atoms is desired to alter the physicochemical properties of target molecules. It is primarily utilized by pharmaceutical research and agrochemical development sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, especially in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Research: Acts as a monomer or precursor for synthesizing specialty polymers and coatings with unique surface properties, such as oil and water repellency.
• Liquid Crystal & OLED Materials: Employed in the development of fluorinated components for electronic display technologies and organic light-emitting diodes.
• Chemical Biology Probes: Useful for creating labeled compounds and probes for studying biological mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	n-{[3-(Trifluoromethyl)Phenyl]Methyl}Prop-2-Enamide
CAS No.	1155979-78-4
Molecular Formula	C11H10F3NO
Molecular Weight	229.20 g/mol
Synonyms	N-[(3-(Trifluoromethyl)phenyl)methyl]acrylamide; 1-[3-(Trifluoromethyl)phenyl]-N-(prop-2-enoyl)methanamine; 3-(Trifluoromethyl)benzylacrylamide; Acrylic acid amide, N-[[3-(trifluoromethyl)phenyl]methyl]-; N-(3-Trifluoromethylbenzyl)acrylamide; Acrylamide, N-[(3-(trifluoromethyl)phenyl)methyl]-; (3-Trifluoromethylbenzyl)acrylamide
EINECS	Contact for details

Quality Control

Our n-{[3-(Trifluoromethyl)Phenyl]Methyl}Prop-2-Enamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.