Description

1-Acetyl-Piperidine-4-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a critical building block in modern synthetic chemistry. Its value lies in its dual reactive sites, enabling its use as a versatile intermediate for constructing complex molecules with specific functionalities. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Chemical Biology Probe Synthesis: Used to create sulfonamide-based probes and inhibitors for studying enzyme function and protein-protein interactions.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science: Employed in the research and development of advanced polymers and functional materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: An essential reagent for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	1-Acetyl-Piperidine-4-Sulfonyl Chloride
CAS No.	1155374-90-5
Molecular Formula	C7H12ClNO3S
Molecular Weight	225.69 g/mol
Synonyms	1-Acetylpiperidine-4-sulfonyl chloride; 4-(Acetylaminopiperidine)-1-sulfonyl chloride; N-Acetyl-4-piperidinesulfonyl chloride; 1-Acetyl-4-piperidinesulfonyl chloride; Piperidine-4-sulfonyl chloride, 1-acetyl-; 4-(Chlorosulfonyl)-1-acetylpiperidine; 1-Acetyl-4-(chlorosulfonyl)piperidine
EINECS	Contact for details

Quality Control

Our 1-Acetyl-Piperidine-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with the standards expected for pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.