Description

Cytochrome P450 14A-Demethylase Inhibitor 1M is a potent and selective small-molecule inhibitor targeting the CYP51 enzyme, a key component in the sterol biosynthesis pathway. This compound is critical for disrupting ergosterol production in fungi and protozoa, offering a valuable tool for biochemical research and drug discovery. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and agrochemical scientists investigating antifungal agents, antiparasitic therapies, and metabolic pathway regulation.

Application

• Biochemical Research: A key tool compound for studying the Cytochrome P450 14α-demethylase (CYP51) enzyme's role in sterol biosynthesis in vitro.
• Antifungal Drug Discovery: Serves as a reference standard and lead compound in the development of novel antifungal agents targeting pathogenic fungi.
• Parasitology Studies: Used in research to investigate new treatments for protozoan infections, such as Chagas disease, by inhibiting ergosterol synthesis in parasites.
• Enzyme Inhibition Assays: Employed in high-throughput screening (HTS) and mechanistic studies to evaluate CYP51 inhibition potency and selectivity.
• Agrochemical Development: Investigated for potential use in developing fungicides that target sterol biosynthesis in plant pathogens.
• Metabolic Pathway Analysis: Facilitates the study of downstream effects of ergosterol depletion on cell membrane integrity and function.

Basic Information

Product Name	Cytochrome P450 14A-Demethylase Inhibitor 1M
CAS No.	1155361-11-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CYP51 Inhibitor 1M; CYP51 Inhibitor; 14α-Demethylase Inhibitor; Sterol 14α-Demethylase Inhibitor; Lanosterol 14α-Demethylase Inhibitor; Antifungal Research Compound 1155361-11-7; Ergosterol Biosynthesis Inhibitor
EINECS	Contact for details

Quality Control

Our Cytochrome P450 14A-Demethylase Inhibitor 1M is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep the container in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 95.0%
Water Content	≤ 0.5%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.