Description

Cytochrome P450 14A-Demethylase Inhibitor 1I is a potent and selective small molecule inhibitor designed to target the CYP51 enzyme, a key component in the sterol biosynthesis pathway. This compound is of significant value for biochemical research and pharmaceutical development, particularly in the study of fungal infections and cholesterol metabolism. It is primarily needed by researchers and developers in the pharmaceutical, biotechnology, and agrochemical industries for target validation, mechanism-of-action studies, and as a lead compound for novel therapeutic agents.

Application

• Biochemical Research: Used as a critical tool compound for in vitro and cell-based assays to study CYP51 enzyme function and inhibition kinetics.
• Antifungal Drug Discovery: Serves as a reference standard and lead molecule in the development of novel azole-class antifungal agents targeting ergosterol synthesis in pathogenic fungi.
• Parasitology Studies: Applied in research targeting Trypanosoma and Leishmania species, where CYP51 is essential for parasite survival.
• Plant Science & Agrochemicals: Investigated for its potential to inhibit sterol biosynthesis in plants, supporting the development of new plant growth regulators or fungicides.
• Mechanistic Toxicology: Employed to understand drug-drug interactions mediated by cytochrome P450 enzymes and to assess compound selectivity profiles.
• High-Throughput Screening (HTS): Utilized as a control or reference inhibitor in screening campaigns to identify new chemical entities with CYP51 inhibitory activity.

Basic Information

Product Name	Cytochrome P450 14A-Demethylase Inhibitor 1I
CAS No.	1155361-07-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CYP51 Inhibitor 1I; CYP14DM Inhibitor 1I; 14-alpha Demethylase Inhibitor 1I; Lanosterol 14-alpha Demethylase Inhibitor 1I; Sterol 14-demethylase Inhibitor 1I; Research Compound 1155361-07-1; Inhibitor 1I (CYP51)
EINECS	Contact for details

Quality Control

Our Cytochrome P450 14A-Demethylase Inhibitor 1I is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and assay results is provided with every shipment to guarantee batch-to-batch consistency and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.