Description

Cytochrome P450 14A-Demethylase Inhibitor 1F is a potent and selective small-molecule inhibitor designed to target the CYP51 enzyme, a key component in the sterol biosynthesis pathway. This compound is of significant value for biochemical research and drug discovery efforts focused on fungal infections and certain metabolic disorders. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in antifungal development, enzyme mechanism studies, and high-throughput screening assays.

Application

• Biochemical Research: Used as a critical tool compound for studying the structure, function, and inhibition kinetics of the Cytochrome P450 14α-demethylase (CYP51) enzyme.
• Antifungal Drug Discovery: Serves as a lead compound or reference standard in the development of novel antifungal agents targeting ergosterol biosynthesis in pathogenic fungi.
• Enzyme Inhibition Assays: Employed in in vitro enzymatic assays to evaluate potency and selectivity against CYP51 and related P450 isoforms.
• Cellular & Microbial Studies: Applied in cell-based models and microbial cultures to investigate the phenotypic consequences of CYP51 inhibition on growth and sterol profiles.
• High-Throughput Screening (HTS): Utilized as a control or validation compound in HTS campaigns to identify new chemotypes with CYP51 inhibitory activity.
• Mechanistic & Target Validation: Supports target validation studies to confirm the therapeutic relevance of CYP51 in specific disease contexts.

Basic Information

Product Name	Cytochrome P450 14A-Demethylase Inhibitor 1F
CAS No.	1155361-04-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CYP51 Inhibitor 1F; CYP14DM Inhibitor 1F; 14α-Demethylase Inhibitor 1F; Lanosterol 14α-demethylase Inhibitor 1F; Sterol 14α-demethylase Inhibitor 1F; Antifungal Research Compound 1F; P450(14DM) Inhibitor 1F
EINECS	Contact for details

Quality Control

Our Cytochrome P450 14A-Demethylase Inhibitor 1F is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes rigorous analytical testing, including purity assessment by HPLC and structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and assay results is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 98%
Water Content	≤ 1.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.