Description

Cytochrome P450 14A-Demethylase Inhibitor 1E is a potent and selective small molecule inhibitor targeting the CYP51 enzyme, a key component in sterol biosynthesis. This compound is of significant value for researchers investigating fungal biology, parasitic infections, and cholesterol metabolism pathways. It is primarily needed by pharmaceutical R&D teams, academic institutions, and biotechnology companies focused on developing novel antifungal agents, antiparasitic drugs, and metabolic disorder therapeutics.

Application

• Antifungal Research: A critical tool for studying the inhibition of ergosterol synthesis in pathogenic fungi, aiding in the discovery of new antifungal drugs.
• Parasitology Studies: Used in research targeting Trypanosoma and Leishmania parasites, where CYP51 is essential for their survival.
• Biochemical Assay Development: Serves as a reference standard and positive control in high-throughput screening (HTS) assays for CYP51 activity.
• Mechanism of Action (MoA) Studies: Enables detailed investigation into sterol 14α-demethylase function and its role in cell membrane integrity.
• Drug Discovery & Medicinal Chemistry: Provides a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Academic & Institutional Research: Supports fundamental research in biochemistry, molecular biology, and infectious disease.

Basic Information

Product Name	Cytochrome P450 14A-Demethylase Inhibitor 1E
CAS No.	1155361-03-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CYP51 Inhibitor 1E; Sterol 14α-Demethylase Inhibitor 1E; CYP14DM Inhibitor 1E; (Chemical Name Pending); Research Compound 1155361-03-7; Lanosterol 14α-Demethylase Inhibitor; Antifungal Research Agent 1E
EINECS	Contact for details

Quality Control

Our Cytochrome P450 14A-Demethylase Inhibitor 1E is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical characterization, including purity verification and identity confirmation. Certificates of Analysis (COA) detailing specific test results are provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.