Description

Cytochrome P450 14A-Demethylase Inhibitor 1C is a potent and selective small molecule inhibitor targeting the CYP51 enzyme, a key component in sterol biosynthesis. This compound is of significant value for research into fungal and parasitic infections, as well as for studying cholesterol metabolism pathways. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on developing novel antifungal agents and investigating cytochrome P450 enzyme function.

Application

• Antifungal Research: A key tool for studying the inhibition of ergosterol synthesis in pathogenic fungi, aiding in the discovery of new therapeutic candidates.
• Parasitology Studies: Used in research targeting Trypanosoma and Leishmania species, where CYP51 is essential for parasite survival.
• Enzyme Mechanism Investigation: Serves as a specific probe to understand the structure-activity relationship and catalytic mechanism of the cytochrome P450 14α-demethylase family.
• Biochemical Assay Development: Employed as a reference standard in high-throughput screening (HTS) assays to identify and characterize new CYP51 inhibitors.
• Metabolic Pathway Analysis: Facilitates research into sterol biosynthesis disruptions in various biological systems, including plant and mammalian cell cultures.
• Preclinical Drug Development: Provides a lead compound for medicinal chemistry optimization programs aimed at improving pharmacokinetic properties and efficacy.

Basic Information

Product Name	Cytochrome P450 14A-Demethylase Inhibitor 1C
CAS No.	1155361-01-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CYP51 Inhibitor 1C; 14α-Demethylase Inhibitor 1C; Sterol 14α-Demethylase Inhibitor; Lanosterol 14α-Demethylase Inhibitor; Antifungal Research Compound 1155361-01-5; CYP450 14DM Inhibitor; Azole-based CYP51 Inhibitor (Structural Class)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and potency. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to strict internal quality protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.