Description

Cytochrome P450 14A-Demethylase Inhibitor 1B is a potent and selective small molecule inhibitor targeting the CYP51 enzyme, a key component in the sterol biosynthesis pathway. This compound is of significant value for researchers investigating fungal biology, parasitic infections, and cholesterol metabolism, offering a precise tool for pathway modulation. It is primarily needed by pharmaceutical R&D teams, academic institutions, and biotechnology companies focused on developing novel antifungal agents, antiparasitic drugs, and exploring new therapeutic targets in metabolic disorders.

Application

• Antifungal Research: A critical tool for studying the mechanism of action of azole-class antifungals and for screening novel compounds against Candida, Aspergillus, and other pathogenic fungi.
• Parasitology Studies: Used in research targeting Trypanosoma and Leishmania species, where CYP51 is essential for parasite survival, aiding in the discovery of new antiprotozoal treatments.
• Biochemical Pathway Analysis: Enables precise inhibition of lanosterol 14α-demethylase to study downstream effects on sterol profiles and membrane integrity in various biological systems.
• Drug Discovery & Development: Serves as a reference standard and a lead compound in medicinal chemistry programs aimed at optimizing selectivity and potency for clinical candidates.
• Agricultural Fungicide Research: Investigated for potential applications in developing new agrochemicals to combat plant fungal diseases by targeting fungal-specific sterol synthesis.

Basic Information

Product Name	Cytochrome P450 14A-Demethylase Inhibitor 1B
CAS No.	1155361-00-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CYP51 Inhibitor 1B; Lanosterol 14-alpha Demethylase Inhibitor; Sterol Biosynthesis Inhibitor; Antifungal Research Compound; CYP450 14DM Inhibitor; CAS 1155361-00-4; Research Inhibitor 1B
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and potency. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) and spectroscopic confirmation are available upon request to support your research and development documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.