Description

1-Benzyl-1H-Pyrazole-4-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a key synthetic intermediate. Its primary value lies in enabling the efficient introduction of the sulfonamide functional group, a crucial motif in modern medicinal chemistry and material science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of drug candidates containing sulfonamide groups, particularly in kinase inhibitors, antibacterial agents, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the sulfonamide moiety imparts desired biological activity.
• Chemical Biology & Proteomics: Serves as a reactive handle for bioconjugation, labeling proteins, or creating activity-based probes (ABPs) due to its selectivity for amine groups.
• Material Science Research: Employed in the synthesis of functional polymers, dyes, and advanced organic materials that require sulfonamide linkages.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	1-Benzyl-1H-Pyrazole-4-Sulfonyl Chloride
CAS No.	1153041-98-5
Molecular Formula	C10H9ClN2O2S
Molecular Weight	256.71 g/mol
Synonyms	1-Benzyl-1H-pyrazole-4-sulfonyl chloride; 1-Benzylpyrazole-4-sulfonyl chloride; 4-(Chlorosulfonyl)-1-benzyl-1H-pyrazole; 1-Benzyl-4-(chlorosulfonyl)-1H-pyrazole; 1H-Pyrazole-4-sulfonyl chloride, 1-benzyl-; 1153041-98-5; Benzylpyrazole sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 1-Benzyl-1H-Pyrazole-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.