Description

8-Oxo-5,6,7,8-Tetrahydronaphthalene-2-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the sulfonamide functional group, a key moiety in the development of active pharmaceutical ingredients and specialty chemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for complex molecular construction.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its sulfonamide-forming capability.
• Material Science Research: Employed in the creation of specialty polymers and functional materials where sulfonamide linkages impart specific thermal or chemical resistance properties.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of chemical probes to study enzyme function and protein interactions.
• Dye & Pigment Manufacturing: Serves as an intermediate in the synthesis of complex organic dyes and colorants.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke molecules for client projects.

Basic Information

Product Name	8-Oxo-5,6,7,8-Tetrahydronaphthalene-2-Sulfonyl Chloride
CAS No.	1152559-02-8
Molecular Formula	C10H9ClO3S
Molecular Weight	244.69 g/mol
Synonyms	5,6,7,8-Tetrahydro-8-oxonaphthalene-2-sulfonyl chloride; 8-Oxo-5,6,7,8-tetrahydronaphthalene-2-sulfonyl chloride; 2-Sulfonylchloride-8-oxo-1,2,3,4-tetrahydronaphthalene; Tetralone-2-sulfonyl chloride; 8-Oxotetralin-2-sulfonyl chloride; 2-(Chlorosulfonyl)-5,6,7,8-tetrahydro-1-naphthalenone; 5,6,7,8-Tetrahydro-8-oxo-2-naphthalenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 8-Oxo-5,6,7,8-Tetrahydronaphthalene-2-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.