Description

1-(2-Fluorobenzyl)-4-Methyl-1H-Pyrazol-5-Amine is a high-purity, fluorinated pyrazole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a fluorinated heterocyclic moiety into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the fluorobenzyl-pyrazole structure confers specific biological activity and stability.
• Chemical Research & Development: Serves as a versatile scaffold for constructing complex heterocyclic libraries in combinatorial chemistry and for structure-activity relationship (SAR) studies.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its nitrogen donor atoms and aromatic system.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials, dyes, and photoactive compounds.

Basic Information

Product Name	1-(2-Fluorobenzyl)-4-Methyl-1H-Pyrazol-5-Amine
CAS No.	1152525-04-6
Molecular Formula	C11H12FN3
Molecular Weight	205.23 g/mol
Synonyms	4-Methyl-1-[(2-fluorophenyl)methyl]-1H-pyrazol-5-amine; 1-[(2-Fluorophenyl)methyl]-4-methyl-1H-pyrazol-5-amine; 5-Amino-1-(2-fluorobenzyl)-4-methyl-1H-pyrazole; 1-(2-Fluorobenzyl)-4-methyl-1H-pyrazol-5-ylamine; 1152525-04-6; 1H-Pyrazol-5-amine, 1-[(2-fluorophenyl)methyl]-4-methyl-
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorobenzyl)-4-Methyl-1H-Pyrazol-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.