Description

5-Methyl-2,1,3-Benzoxadiazole-4-Sulfonyl Chloride (Saltdata: Free) is a high-purity sulfonyl chloride derivative, a key synthetic intermediate in modern organic chemistry. Its primary value lies in its reactivity as a versatile sulfonylation reagent, enabling the efficient introduction of the sulfonyl functional group into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and fine chemicals requiring specific sulfonamide linkages. The CAS number for this product is 1152431-76-9.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the sulfonyl moiety enhances biological activity.
• Peptide Modification & Bioconjugation: Serves as a reagent for selectively modifying amino acid side chains (e.g., cysteine, lysine) in peptides and proteins for research and therapeutic applications.
• Material Science & Polymer Chemistry: Employed to create functional monomers and polymers with specific sulfonyl groups, imparting desired properties like thermal stability or solubility.
• Dye & Pigment Manufacturing: Acts as a precursor in the synthesis of specialized dyes and colorants for technical applications.
• Chemical Research & Development: A valuable tool for medicinal chemists and process development scientists exploring new synthetic routes and molecular entities.

Basic Information

Product Name	5-Methyl-2,1,3-Benzoxadiazole-4-Sulfonyl Chloride (Saltdata: Free)
CAS No.	1152431-76-9
Molecular Formula	C7H5ClN2O3S
Molecular Weight	232.64 g/mol
Synonyms	5-Methylbenzo[c][1,2,5]oxadiazole-4-sulfonyl chloride; 5-Methyl-2,1,3-benzoxadiazole-4-sulfonyl chloride; 4-(Chlorosulfonyl)-5-methyl-2,1,3-benzoxadiazole; 5-Methyl-2,1,3-benzoxadiazole-4-sulfonchlorid; 5-Methylbenzofurazan-4-sulfonyl chloride; 5-Methyl-4-sulfonylchloride-2,1,3-benzoxadiazole
EINECS	Contact for details

Quality Control

Our 5-Methyl-2,1,3-Benzoxadiazole-4-Sulfonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent specifications. We support cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.