Description

2,3-Difluoro-5-(1-Methyl-1H-Pyrazol-4-Yl)Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound matters as a critical intermediate for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorinated pyridine motifs into their target structures.

Application

This versatile fluorinated pyridine derivative serves as a key synthetic intermediate in several high-tech applications:

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the difluoropyridine moiety enhances biological activity and stability.
• Material Science Research: Employed in the development of organic electronic materials, ligands for catalysis, and advanced polymers.
• Chemical Biology Probes: Serves as a scaffold for creating fluorescent tags or molecular probes for biochemical research.
• Cross-Coupling Reactions: The pyrazolyl and halogenated pyridine groups make it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	2,3-Difluoro-5-(1-Methyl-1H-Pyrazol-4-Yl)Pyridine
CAS No.	1151801-90-9
Molecular Formula	C9H7F2N3
Molecular Weight	195.17 g/mol
Synonyms	5-(1-Methyl-1H-pyrazol-4-yl)-2,3-difluoropyridine; 2,3-Difluoro-5-(1-methyl-1H-pyrazol-4-yl)pyridine; 2,3-Difluoro-5-(1-methylpyrazol-4-yl)pyridine; 1151801-90-9; 5-(1-Methyl-1H-pyrazol-4-yl)-2,3-difluoropyridine; Pyridine, 2,3-difluoro-5-(1-methyl-1H-pyrazol-4-yl)-
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-5-(1-Methyl-1H-Pyrazol-4-Yl)Pyridine is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for research and scale-up applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.