Description

2-Methyl-4-(trifluoromethyl)-1,3-thiazole-5-sulfonyl chloride, 97% is a high-purity, reactive organosulfur building block essential for advanced synthetic chemistry. Its core value lies in the sulfonyl chloride functional group, which enables efficient introduction of the sulfonamide moiety, a key pharmacophore in modern drug discovery. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor for synthesizing sulfonamide-based drug candidates targeting a wide range of diseases.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a building block for creating functional polymers and advanced organic materials.
• Chemical Biology Probes: Employed in the design of activity-based probes for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A key reagent for fine chemical suppliers offering bespoke synthesis services.

Basic Information

Item	Detail
Product Name	2-Methyl-4-(trifluoromethyl)-1,3-thiazole-5-sulfonyl chloride, 97%
CAS No.	1151512-22-9
Molecular Formula	C5H3ClF3NO2S2
Molecular Weight	265.66 g/mol
Synonyms	5-(Chlorosulfonyl)-2-methyl-4-(trifluoromethyl)thiazole; 2-Methyl-4-trifluoromethyl-1,3-thiazole-5-sulfonyl chloride; 4-(Trifluoromethyl)-2-methylthiazole-5-sulfonyl chloride; 2-Methyl-4-(trifluoromethyl)thiazole-5-sulfonyl chloride; 5-Chlorosulfonyl-2-methyl-4-trifluoromethylthiazole; 1151512-22-9; Thiazole-5-sulfonyl chloride, 2-methyl-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of our 2-Methyl-4-(trifluoromethyl)-1,3-thiazole-5-sulfonyl chloride is produced and tested under a strict quality management system. We guarantee a minimum purity of 97% (typically by HPLC), with rigorous control of moisture and related impurities. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profile is provided with each shipment to ensure traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.