Description

Potassium 5-Fluoropyridine-2-trifluoroborate is a high-purity organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling robust and selective cross-coupling reactions, particularly Suzuki-Miyaura couplings, due to its enhanced stability and handling compared to traditional boronic acids. This advanced intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: A key synthon for introducing the 5-fluoropyridyl moiety into active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced fluorinated pesticides and herbicides.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable organoboron reagent for palladium-catalyzed carbon-carbon bond formation to create complex biaryl structures.
• Material Science Research: Employed in the development of fluorinated organic electronic materials, ligands, and liquid crystals.
• Chemical Biology & Probe Development: Useful for synthesizing fluorinated molecular probes and tags for imaging and diagnostic applications.
• Process Chemistry & Scale-up: Provides a reliable and scalable route for the industrial manufacture of fluorinated fine chemicals.

Basic Information

Product Name	Potassium 5-Fluoropyridine-2-trifluoroborate
CAS No.	1150654-92-4
Molecular Formula	C5H3BF4KN
Molecular Weight	207.89 g/mol
Synonyms	Potassium (5-Fluoropyridin-2-yl)trifluoroborate; 5-Fluoropyridine-2-trifluoroborate Potassium Salt; 2-(5-Fluoropyridyl)trifluoroboronate Potassium; Potassium 5-Fluoro-2-pyridyltrifluoroborate; 5-Fluoro-2-pyridyltrifluoroboronic acid potassium salt; (5-Fluoropyridin-2-yl)trifluoroboronic acid potassium salt; K-5F-2-PyBF3
EINECS	Contact for details

Quality Control

Our Potassium 5-Fluoropyridine-2-trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹⁹F, ¹¹B), HPLC, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere (argon/nitrogen) when opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹H NMR Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.