Description

4-Bromo-2-Fluoropyridine-3-Boronicacidpinacolester is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing fluorinated pyridine motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Employed in the creation of organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical boronic ester coupling partner for introducing the 4-bromo-2-fluoropyridine moiety into complex molecular architectures.
• Chemical Biology & Proteomics: Utilized as a versatile handle for bioconjugation and the development of molecular probes.
• Ligand Synthesis: Precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Bromo-2-Fluoropyridine-3-Boronicacidpinacolester
CAS No.	1150561-79-7
Molecular Formula	C11H14BBrFNO2
Molecular Weight	300.95 g/mol
Synonyms	4-Bromo-2-fluoro-3-pyridineboronic acid pinacol ester; 2-Fluoro-4-bromopyridine-3-boronic acid pinacol ester; (4-Bromo-2-fluoropyridin-3-yl)boronic acid pinacol ester; 3-Boronicacidpinacolester, 4-Bromo-2-fluoropyridine-; 4-Bromo-2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 1150561-79-7; BRN 15320481
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoropyridine-3-Boronicacidpinacolester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, as boronic esters can be moisture-sensitive.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.