Description

2-Fluoro-6-(Trifluoromethyl)Pyridine-3-Boronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling the efficient construction of complex fluorinated pyridine derivatives through reliable cross-coupling reactions. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for Suzuki-Miyaura cross-coupling reactions in the synthesis of drug candidates, particularly those targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used to create advanced fluorinated pyridine-based herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a precursor for developing novel fluorinated liquid crystals, organic semiconductors, and advanced polymers.
• Chemical Biology Probes: Enables the synthesis of fluorinated molecular probes and tags for imaging and diagnostic applications.
• Catalyst Ligand Development: Utilized in the preparation of specialized ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-6-(Trifluoromethyl)Pyridine-3-Boronic Acid
CAS No.	1150114-63-8
Molecular Formula	C7H4BF4NO2
Molecular Weight	208.92 g/mol
Synonyms	2-Fluoro-6-(trifluoromethyl)-3-pyridineboronic acid; [2-Fluoro-6-(trifluoromethyl)pyridin-3-yl]boronic acid; 3-Borono-2-fluoro-6-(trifluoromethyl)pyridine; 2-Fluoro-6-trifluoromethylpyridine-3-boronic acid; 2-Fluoro-6-(trifluoromethyl)-3-pyridinylboronic acid; 1150114-63-8; B-[2-Fluoro-6-(trifluoromethyl)-3-pyridinyl]boronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(Trifluoromethyl)Pyridine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.