Description

2-Fluoro-4-Nitrobenzene-1-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to act as a sulfonylation reagent, introducing the sulfonyl functional group to create novel compounds with specific properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific sulfonyl group chemistry.
• Material Science Research: Building block for creating specialty polymers, dyes, and liquid crystals with tailored electronic or optical properties.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling or modifying biomolecules in research applications.
• Custom Synthesis & Contract Manufacturing: A high-value intermediate for fine chemical companies offering bespoke synthesis services.

Basic Information

Product Name	2-Fluoro-4-Nitrobenzene-1-Sulfonyl Chloride
CAS No.	1146290-36-9
Molecular Formula	C6H3ClFNO4S
Molecular Weight	239.61 g/mol
Synonyms	2-Fluoro-4-nitrobenzenesulfonyl chloride; 4-Nitro-2-fluorobenzenesulfonyl chloride; 1-(Chlorosulfonyl)-2-fluoro-4-nitrobenzene; 2-Fluoro-4-nitrobenzene sulfonyl chloride; 2-Fluoro-4-nitro-1-sulfonyl chloride benzene; 2-Fluoro-4-nitrobenzenesulphonyl chloride; 2-Fluoro-4-nitrophenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-Nitrobenzene-1-Sulfonyl Chloride is produced and tested under strict quality management protocols. We ensure compliance with high-purity standards suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.