Description

1-(1,1-Difluoropropyl)-2-Fluorobenzene is a specialized fluorinated aromatic compound of significant interest in advanced organic synthesis. Its unique difluoropropyl side chain adjacent to a fluorinated benzene ring makes it a valuable high-purity building block for the development of novel molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating new active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorine atoms to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atoms can improve activity and environmental profile.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials with specific fluorinated properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecules via cross-coupling reactions or as a source of difluorinated motifs.
• Fluorine Chemistry Studies: Used as a model compound or reagent in methodological research focused on new fluorination techniques or reaction pathways.

Basic Information

Product Name	1-(1,1-Difluoropropyl)-2-Fluorobenzene
CAS No.	1138445-47-2
Molecular Formula	C9H9F3
Molecular Weight	174.16 g/mol
Synonyms	2-Fluoro-1-(1,1-difluoropropyl)benzene; 1-(1,1-Difluoropropyl)-2-fluorobenzene; o-Fluoro-α,α-difluoropropylbenzene; Benzene, 1-(1,1-difluoropropyl)-2-fluoro-; 2-Fluorobenzene, 1-(1,1-difluoropropyl)-; (2-Fluorophenyl)(1,1-difluoropropyl)methane
EINECS	Contact for details

Quality Control

Our 1-(1,1-Difluoropropyl)-2-Fluorobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable for advanced intermediates, ensuring the material meets the stringent requirements of research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from incompatible materials such as strong bases. Due to its highly volatile nature, ensure containers are kept tightly sealed and at a consistent temperature, ideally between 15-25°C. Handle and store under an inert atmosphere if specified for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Related Substances (GC/HPLC)	Total impurities ≤3.0%
Density	~1.15 g/cm³ (at 20°C)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.