Description

1-(1,1-Difluoroethyl)-2-Fluoro-4-(Trifluoromethyl)Benzene is a high-value, multi-fluorinated aromatic building block essential for advanced chemical synthesis. This compound is prized for its unique structure, which introduces significant steric and electronic effects, making it a critical intermediate in the development of novel active ingredients. It is primarily sought by R&D and process chemistry teams in the pharmaceutical and agrochemical sectors for creating next-generation compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the difluoroethyl and trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a fluorinated core structure in the synthesis of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs), improving performance characteristics.
• Polymer & Material Science: Acts as a monomer or modifier in the creation of high-performance, fluorinated polymers with exceptional chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions and as a ligand precursor in catalytic systems, leveraging its electron-deficient aromatic ring.
• R&D for Fluorine Chemistry: An important reference compound and starting material in academic and industrial research focused on exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Product Name	1-(1,1-Difluoroethyl)-2-Fluoro-4-(Trifluoromethyl)Benzene
CAS No.	1138445-16-5
Molecular Formula	C9H6F6
Molecular Weight	228.14 g/mol
Synonyms	2-Fluoro-α,α-difluoro-4-(trifluoromethyl)toluene; 1-(1,1-Difluoroethyl)-2-fluoro-4-(trifluoromethyl)benzene; 1-(2-Fluoro-4-(trifluoromethyl)phenyl)-1,1-difluoroethane; α,α-Difluoro-2-fluoro-4-(trifluoromethyl)toluene; 2-Fluoro-4-(trifluoromethyl)benzene, 1-(1,1-difluoroethyl)-; 1-(Difluoroethyl)-2-fluoro-4-(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our 1-(1,1-Difluoroethyl)-2-Fluoro-4-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for pharmaceutical and advanced material research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.