Description

1-(1,1-Difluoroethyl)-3,5-Difluorobenzene is a high-value fluorinated aromatic building block, essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs). Its unique structure, featuring a difluoroethyl side chain on a difluorobenzene core, makes it a critical intermediate for introducing specific fluorine motifs that enhance the metabolic stability, lipophilicity, and bioavailability of target molecules. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty materials sectors for creating next-generation products.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in oncology, CNS, and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where fluorine substitution improves efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystals used in high-performance displays (LCDs).
• Organic Electronics: Employed in the synthesis of semiconductors and charge-transport materials for OLEDs and organic photovoltaics.
• Fluorinated Polymer Modification: Acts as a monomer or modifier to impart specific chemical resistance, low surface energy, or thermal stability to advanced polymers.
• Positron Emission Tomography (PET) Tracers: Potential use as a precursor for fluorine-18 labeled radiopharmaceuticals for medical imaging.

Basic Information

Item	Detail
Product Name	1-(1,1-Difluoroethyl)-3,5-Difluorobenzene
CAS No.	1138445-10-9
Molecular Formula	C10H8F4
Molecular Weight	204.17 g/mol
Synonyms	3,5-Difluoro-1-(1,1-difluoroethyl)benzene; 1-(1,1-Difluoroethyl)-3,5-difluorobenzene; 3,5-Difluoro-alpha,α-difluoroethylbenzene; (1,1-Difluoroethyl)-3,5-difluorobenzene; Benzene, 1-(1,1-difluoroethyl)-3,5-difluoro-; 3,5-Difluorobenzene, 1-(1,1-difluoroethyl)-; α,α,3,5-Tetrafluoroethylbenzene
EINECS	Contact for details

Quality Control

Every batch of 1-(1,1-Difluoroethyl)-3,5-Difluorobenzene is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including GC, HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizers, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.