Description

2-(1,1-Difluoroethyl)-1,4-Difluorobenzene is a high-value fluorinated aromatic building block, essential for introducing specific fluorine substitution patterns into advanced molecular architectures. Its precise structure offers unique electronic and steric properties, making it a critical intermediate for developing novel materials and active compounds. This product is primarily needed by R&D and process development teams in the pharmaceutical, agrochemical, and specialty materials industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs where its difluoroethyl and difluorobenzene motifs can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorine atoms are crucial for improving efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Specialty Chemicals: Acts as a monomer or modifier in the creation of high-performance polymers with enhanced chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions and other catalytic processes for constructing complex fluorinated organic molecules in academic and industrial research.

Basic Information

Product Name	2-(1,1-Difluoroethyl)-1,4-Difluorobenzene
CAS No.	1138445-05-2
Molecular Formula	C8H6F4
Molecular Weight	178.13 g/mol
Synonyms	1,4-Difluoro-2-(1,1-difluoroethyl)benzene; 2-(1,1-Difluoroethyl)-1,4-difluorobenzene; 1,4-Difluoro-2-(α,α-difluoroethyl)benzene; α,α,2,5-Tetrafluorotoluene; 1-(2,5-Difluorophenyl)-1,1-difluoroethane; Benzene, 1,4-difluoro-2-(1,1-difluoroethyl)-; (1,1-Difluoroethyl)-2,5-difluorobenzene
EINECS	Contact for details

Quality Control

Our 2-(1,1-Difluoroethyl)-1,4-Difluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.