Description

(5Z)-n-(Cyclopropylmethyl)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-Hydroxy-4-Phenoxy-1-Buten-1-Yl]Cyclopentyl]-5-Heptenamide is a sophisticated synthetic prostaglandin analog, representing a high-value intermediate in advanced pharmaceutical research and development. Its complex stereochemistry and functional groups make it a critical building block for creating novel therapeutic agents targeting specific biological pathways. This compound is essential for researchers and manufacturers in the pharmaceutical industry, particularly those focused on developing new drugs in areas such as ophthalmology, cardiovascular health, and inflammation.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel prostaglandin-based active pharmaceutical ingredients (APIs).
• Ophthalmic Drug Development: Used in research for developing next-generation glaucoma and ocular hypertension treatments.
• Cardiovascular Research: Investigated as a building block for compounds targeting vascular tone and platelet aggregation.
• Inflammation & Immunology Studies: Employed in the discovery of new anti-inflammatory agents and immunomodulators.
• Chemical Biology Probes: Utilized to create tools for studying prostaglandin receptor function and signaling pathways.
• Process Chemistry & Scale-Up: Acts as a reference standard and intermediate for optimizing synthetic routes in pilot and commercial manufacturing.

Basic Information

Product Name	(5Z)-n-(Cyclopropylmethyl)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-Hydroxy-4-Phenoxy-1-Buten-1-Yl]Cyclopentyl]-5-Heptenamide
CAS No.	1138395-09-1
Molecular Formula	C26H37NO6
Molecular Weight	459.58 g/mol
Synonyms	PF-04217329 (Prostamide Agonist); Travoprost Cyclopropylmethyl Amide; CPMA; (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl]cyclopentyl]-N-(cyclopropylmethyl)-5-heptenamide; PF 04217329; PF04217329; AGN 211377; AGN-211377
EINECS	Contact for details

Quality Control

Our (5Z)-n-(Cyclopropylmethyl)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-Hydroxy-4-Phenoxy-1-Buten-1-Yl]Cyclopentyl]-5-Heptenamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.