Description

2-Bromo-1-(2-Fluoropyridin-3-Yl)Ethanone Hydrobromide is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate functionalized pyridine motifs into complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Synthesis: Intermediate for developing new generation pesticides and herbicides with enhanced efficacy.
• Chemical Biology Probes: Serves as a precursor for creating labeled compounds or probes used in biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.
• Academic Research: Used in university and institutional labs for organic methodology development and heterocyclic chemistry studies.

Basic Information

Product Name	2-Bromo-1-(2-Fluoropyridin-3-Yl)Ethanone Hydrobromide
CAS No.	1138033-53-0
Molecular Formula	C7H6Br2FNO
Molecular Weight	308.94 g/mol
Synonyms	2-Bromo-1-(2-fluoropyridin-3-yl)ethan-1-one hydrobromide; 3-Acetyl-2-fluoropyridine Hydrobromide, 2-Bromo Derivative; 2-Fluoro-3-(2-bromoacetyl)pyridine Hydrobromide; α-Bromo-2-fluoro-3-pyridyl methyl ketone HBr; 1-(2-Fluoropyridin-3-yl)-2-bromoethanone Hydrobromide; 2-Bromo-1-(2-fluoro-3-pyridinyl)ethanone HBr Salt
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(2-Fluoropyridin-3-Yl)Ethanone Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates for research and regulated development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.