Description

Gdc-0834 (Racemate) is a small molecule research compound with the CAS registry number 1133432-46-8. This chemical serves as a valuable intermediate and reference standard in the discovery and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and biotechnology companies focused on oncology and immunology research.

Application

• Pharmaceutical Research & Development: A key intermediate in the synthesis of novel drug candidates targeting specific kinase pathways.
• Biochemical Screening: Used as a reference standard or active pharmaceutical ingredient (API) impurity standard in high-throughput screening assays.
• Preclinical Studies: Employed in in vitro and in vivo studies to investigate pharmacokinetic and pharmacodynamic properties.
• Process Chemistry: Serves as a building block for medicinal chemists during structure-activity relationship (SAR) optimization.
• Analytical Reference: Provides a critical racemic standard for method development and validation in analytical laboratories (HPLC, LC-MS).
• Academic Research: Used in university and institutional labs for fundamental research in chemical biology and signal transduction.

Basic Information

Product Name	Gdc-0834 (Racemate)
CAS No.	1133432-46-8
Molecular Formula	C₂₀H₂₀N₆O₂
Molecular Weight	376.42 g/mol
Synonyms	GDC-0834; GDC0834; (Rac)-GDC-0834; N-[3-[[5-Fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]phenyl]-2-propenamide; UNII-8J8N517V6S; 8J8N517V6S; GDC-0834 Racemate; GDC 0834 (racemic)
EINECS	Contact for details

Quality Control

Our Gdc-0834 (Racemate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.