Description

1-Difluoromethyl-2-Oxo-1,2-Dihydro-Pyridine-3-Carboxylic Acid is a high-value, fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of a difluoromethyl group can significantly alter biological activity and metabolic stability. Its primary utility lies in the pharmaceutical and agrochemical R&D sectors, enabling the creation of next-generation therapeutics and crop protection agents with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where fluorination improves efficacy and environmental profile.
• Chemical Research & Development: Serves as a versatile precursor for constructing complex heterocyclic frameworks in medicinal and process chemistry.
• Material Science: Potential application in the synthesis of specialty polymers and advanced materials requiring fluorinated components.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up.

Basic Information

Item	Details
Product Name	1-Difluoromethyl-2-Oxo-1,2-Dihydro-Pyridine-3-Carboxylic Acid
CAS No.	1129458-32-7
Molecular Formula	C7H5F2NO3
Molecular Weight	189.12 g/mol
Synonyms	1-(Difluoromethyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 1-(difluoromethyl)-1,2-dihydro-2-oxo-; 1-Difluoromethyl-2-oxo-1,2-dihydro-3-pyridinecarboxylic acid; 1,2-Dihydro-1-(difluoromethyl)-2-oxo-3-pyridinecarboxylic acid; DFMPA (abbreviation); Difluoromethyl DHPC Acid
EINECS	Contact for details

Quality Control

Every batch of 1-Difluoromethyl-2-Oxo-1,2-Dihydro-Pyridine-3-Carboxylic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.