Description

Prasugrel-D5 is a deuterated stable isotope-labeled analog of the antiplatelet drug Prasugrel, specifically designed for use as an internal standard in quantitative bioanalytical methods. This high-purity compound is essential for ensuring the accuracy and reliability of pharmacokinetic and metabolism studies, providing critical data for drug development and regulatory submissions. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in advanced LC-MS/MS analysis.

Application

• Primary use as an internal standard for the precise quantification of Prasugrel and its metabolites in biological matrices (e.g., plasma, serum) via LC-MS/MS.
• Critical component in pharmacokinetic (PK) and pharmacodynamic (PD) studies during clinical trials for antiplatelet therapies.
• Enables accurate drug metabolism and excretion studies by correcting for matrix effects and instrument variability.
• Supports bioequivalence and bioavailability testing for generic drug development.
• Used in forensic and anti-doping analysis for the specific detection of Prasugrel.
• Facilitates method development and validation in accordance with FDA, EMA, and ICH guidelines.

Basic Information

Product Name	Prasugrel-D5
CAS No.	1127252-92-9
Molecular Formula	C20H15D5FNO3S
Molecular Weight	376.46 g/mol
Synonyms	5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate-d5; (5)-2-Acetoxy-5-(α-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-d5; Prasugrel Deuterated Standard; Prasugrel-d5 Internal Standard; Prasugrel (phenyl-d5); Efient-d5
EINECS	Contact for details

Quality Control

Our Prasugrel-D5 is manufactured under strict quality systems to ensure exceptional isotopic purity and chemical integrity, suitable for the most demanding analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results for isotopic enrichment (D5, typically >98%), chemical purity (by HPLC, typically >98%), and identity confirmation (by NMR and MS). We adhere to relevant standards for reference materials, and custom purity grades are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D5)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.