Description

1-(6-Fluoropyridin-3-Yl)Piperazine is a high-value fluorinated piperazine derivative, serving as a critical building block in modern organic synthesis. This compound is essential for research and development in the pharmaceutical sector, where it is used to introduce specific pharmacophores that can enhance drug potency and metabolic stability. Key industries that utilize this intermediate include pharmaceutical R&D, agrochemical development, and advanced material science for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom and piperazine ring contribute to biological activity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Chemical Biology Research: Employed as a probe or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	1-(6-Fluoropyridin-3-Yl)Piperazine
CAS No.	1121610-07-8
Molecular Formula	C9H12FN3
Molecular Weight	181.21 g/mol
Synonyms	1-(6-Fluoropyridin-3-yl)piperazine; 3-Piperazinyl-6-fluoropyridine; 6-Fluoro-3-piperazin-1-ylpyridine; 6-Fluoro-3-(1-piperazinyl)pyridine; 1-(6-Fluoro-3-pyridinyl)piperazine; 6-Fluoro-3-piperazinopyridine; 1121610-07-8
EINECS	Contact for details

Quality Control

Our 1-(6-Fluoropyridin-3-Yl)Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.