Description

(3,5,6-Trifluoropyridin-2-Yl)Acetic Acid CAS NO 1119450-11-1 is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl-substituted pyridine core offers enhanced metabolic stability and lipophilicity, making it indispensable for creating novel active compounds. This intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of next-generation active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-infective drug discovery.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials for specialized applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	(3,5,6-Trifluoropyridin-2-Yl)Acetic Acid
CAS No.	1119450-11-1
Molecular Formula	C7H4F3NO2
Molecular Weight	199.11 g/mol
Synonyms	2-(3,5,6-Trifluoropyridin-2-yl)acetic acid; (3,5,6-Trifluoro-2-pyridyl)acetic acid; 2-(3,5,6-Trifluoropyridin-2-yl)ethanoic acid; 1119450-11-1; TFPA; 3,5,6-Trifluoropicolinic acid derivative
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fluorinated intermediates. Every batch of (3,5,6-Trifluoropyridin-2-Yl)Acetic Acid is analyzed using advanced techniques like HPLC, GC, and NMR to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. Our quality system supports development and cGMP manufacturing requirements for regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.